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Metastatic GIST (initially diagnosed as uterine leiomyosarcoma), Kyiv, Ukraine · records 2022–2026 · updated 14 Oct 2026

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Pathohistological study of the liver metastasis

Date: 2023-04-26   Institution: CSD laboratory, Kyiv   Type: Pathology
Source file (Google Drive, docs_eng/): Pathohistological study_26.04.2023.docx

Pathohistological study

Clinical data
Date and time of operation 25.04.2023 Operation type Liver biopsy.
Pathomorphological conclusion
Diagnosis Metastasis of gastrointestinal stromal tumor in the liver (ICD-O code 8936/3).
Macroscopic description
Amount of blocks 1
A. Columns of gray-brown tissue up to 2 cm long and fragments. There are no remains. A1 – trephine biopsy.
Microscopic description
The material contains columns of liver tissue with the growth of a metastasis of a gastrointestinal stromal tumor. In the immunohistochemical study, the tumor cells are positive for DOG-1, CD117, which allows to confirm the diagnosis.
Immunohistochemical studies

Block 23SP046733 A1:

CD117 (c-kit) (DAKO, polyclonal ones) – a positive reaction in tumor cells;

DOG-1 (Diagnostic Biosystems, clone DOG1.1) is a positive reaction in tumor cells.

O.O. Koshyk
23SP046733 Zherlitsyna Anastasiia Stanislavivna 1/1

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