Neuroradiology second opinion on the brain MRI scans
UNIVERSITY HOSPITAL FREIBURG Clinic for Neuroradiology · Breisacher Straße 64 · 79106 Freiburg University Hospital Freiburg International Medical Services and International Business Development Breisacher Str. 86b 79110 Fribourg File number hu/il Freiburg, 09.02.2023 ZHERLITSYNA, Anastasiia, 25.04.76, 43851462 Clinical question: Malignant uterine tumor. Posterior reversible encephalopathy syndrome (PRES) as a side effect of therapy with Votrient. MRI of the head from 20.01.2023, 20.09.2022: Measurement technique: sagittal T1 MPRAGE 1 mm, axial DWI, axial 3D-TOF-MRA axial T2 TSE, coronary TWIST, axial T1 MPRAGE 1 mm after contrast administration Diffusion disorders occipital on both sides and parietal along the edge of the mantle. Circumscribed, about 15 mm in size, Parenchymal hemorrhage on the left occipital above the calcarine fissure and spot-shaped hemorrhages on the right occipital. Caliber irregularities with narrowing of the middle cerebral artery on both sides. |
Department Neuro Center Neuroradiology Clinic Medical Director Prof. Dr. Horst Urbach Phone 0761 270-51810 Fax 0761 270-51950 horst.urbach@uniklinik-freiburg.de http://www.uniklinik-freiburg.de/neuroradiologie.html Functional areas: Assistant manager Iris Lopez 0761 270-51810 iris.lopez@uniklinik-freiburg.de Lead MTRA Marta Fuhl 0761 270-51940 marta.fuhl@uniklinik-freiburg.de Patient management 0761 270-51710 0761 270-51140 (fax) patientenmanagement-nrad@uniklinik-freiburg.de Senior doctor's secretariat Mandy Meier 0761 270-51720 mandy.meier@uniklinik-freiburg.de |
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MRI of the head from 13.01.2023:
Measurement technique: axial T1 MPRAGE 1 mm after contrast administration
Multiple cortical speckled contrast images with parieto-occipital emphasis and emphasis in the right superior frontal sulcus.
MRI of the head from 20.09.2022:
Measurement technique: axial T2, axial DWI, axial T2 STIR, axial T1 fat-sat 3D after contrast agent administration Small DVA right parietal.
Conclusion:
Therapy-associated changes with parieto-occipital diffusion disorders, occipital hemorrhages and constriction of cerebral arteries, including the middle cerebral artery on both sides. These changes are a typical consequence of therapy with tyrosine kinase inhibitors such as Votrient (and can be subsumed under the umbrella term PRES, although narrowing of the arteries is not consistent with PRES).
Best regards
Prof. Dr. Horst Urbach
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