Advisory conclusion (video consultation)
Patient’s name: Zherlitsyna Anastasia Stanislavivna Date of birth: April 25, 1976 ID 110889 |
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ADVISORY CONCLUSION
(zoom consultation)
Diagnosis: Leiomyosarcoma of the uterine body, T2NxM1, secondary damage to the liver, peritoneum. Condition after 4 cycles of chemotherapy according to the Gemcitabine + Docetaxel + Avastin protocol with progression of the disease in the liver (according to CT, MRI from 10/2022). C-KIT, MET (ONCOMINE) mutation was detected. The condition after treatment with Pazopanib (05-12/01/2023) with the development of the posterior reverse encephalopathy syndrome and positive dynamics according to the CT scan.
01/2023 - repeated liver biopsy. Pathohistological conclusion - metastasis of uterine leiomyosarcoma. Condition after 3 cycles of chemotherapy according to the Trabectedin protocol with negative X-ray dynamics (PET/CT from 11/04/2023). Suspicion of the presence of synchronous neoplasia of the stomach (GIST?). Condition after EUS-FNA of gastric biopsy, liver core biopsy, histologically - gastrointestinal stromal tumor (GIST) of the stomach, GIST metastasis in the liver (CSD). Therapy with Imatinib 400 mg per day was started.
Recommended:
Continue treatment with Imatinib at a dose of 400 mg per day with condition control (clinical examination + CT scan in comparison) after 3 months of treatment.
Revision of histological preparations from 08/2022 in the reference laboratory (Frankfurt/CSD) for the purpose of differential diagnosis of uterine leiomyosarcoma and GIST.
This opinion is provided based solely on the material provided by the patient.
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