Anastasia Zherlitsyna — timeline

Metastatic GIST (initially diagnosed as uterine leiomyosarcoma), Kyiv, Ukraine · records 2022–2026 · updated 14 Oct 2026

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Interdisciplinary oncology conference conclusion

Date: 2023-05-03   Institution: LISOD, Kyiv   Type: Tumour board
Source file (Google Drive, docs_eng/): CONCLUSION_oncology conference 03.05.2023.docx

LISOD

Israel Oncology Hospital

08720, Kyiv region, Obukhiv district,

village Plyut, str. Malyshka, 27

phone +38044 520 94 00

fax +38044 520 94 01

www.lisod.ua

CONCLUSION

of the interdisciplinary oncology conference

from May 03, 2023

The conference participants:

Anastasia Stanislavivna Zherlitsina

Apr 25, 1976

ID: 110889

Diagnosis: Leiomyosarcoma of the uterine body, T2NxM1, secondary liver, peritoneum damage.

Condition after 4 cycles of chemotherapy according to the Gemcitabine + Docetaxel + Avastin protocol with progression of the disease in the liver (according to CT, MRI from 10/2022). C-KIT, MET (ONCOMINE) mutation was detected. The condition after treatment with Pazopanib (05-12/01/2023) with the development of the posterior reversible encephalopathy syndrome and positive dynamics according to the CT data.

01/2023 - repeated liver biopsy. Pathohistological conclusion - uterine leiomyosarcoma metastasis. Condition after 3 cycles of chemotherapy according to the Trabectedin protocol with negative X-ray dynamics (PET/CT from 11/04/2023). Suspicion of the presence of synchronous neoplasia of the stomach (GIST?). Condition after EUS-FNA of gastric biopsy, liver core biopsy, histologically - gastrointestinal stromal tumor (GIST) of the stomach, GIST metastasis in the liver (CSD).

Recommended:

Start treatment with Imatinib at a dose of 400 mg per day with condition control (clinical examination + CT scan in comparison) after 3 months of treatment.

Revision of histological preparations from 08/2022 in the reference laboratory (Frankfurt/CSD) for the purpose of differential diagnosis of uterine leiomyosarcoma and GIST.

Evaluating follow-up tactics based on FoundationOne research results.

If you have suggestions or comments about the work of our hospital, please contact us on the "LISOD Hospital Hotline" - 0 800 50 51 58 (toll-free from any phone number within Ukraine).

All recommendations given in this Conclusion are prescribed and should be carried out exclusively under the supervision of a treating physician.