Anastasia Zherlitsyna — timeline

Metastatic GIST (initially diagnosed as uterine leiomyosarcoma), Kyiv, Ukraine · records 2022–2026 · updated 14 Oct 2026

← biopsies and pathology

Pathology of the gastric and liver biopsies of 05.10.2026, Shalimov National Scientific Center of Surgery and Transplantology (English translation)

Biopsy: 2026-10-05   Material received: 2026-10-06   Report: 2026-10-13   Institution: State Institution "O.O. Shalimov National Scientific Center of Surgery and Transplantology", Kyiv, department IV   Type: Pathology

Referral and report on one page, medical documentation form No. 014/o (Форма № 014/о), approved by order of the Ministry of Health of Ukraine of 29.05.2013 No. 435. Electronic document; the signature lines are empty and there are no stamps or handwritten entries.

Institution: Ministry of Health of Ukraine; National Academy of Medical Sciences of Ukraine; State Institution “O.O. Shalimov National Scientific Center of Surgery and Transplantology” (ДУ «Національний науковий центр хірургії та трансплантології імені О.О. Шалімова»), 30 Akademika Shalimova Street, Kyiv.

Referral for pathohistological examination (Направлення на патологогістологічне дослідження)

Field Entry
Material number No. 4222/26
Date and time the material was sent 05.10.26 (no time given)
Department “IV” (Відділення «IV»)
Inpatient medical card (Медична карта стаціонарного хворого) No. 9577
1. Patient Zherlitsyna Anastasiia Stanislavivna (Жерліцина Анастасія Станіславівна)
2. Sex female
3. Age “1971 р.н.” (year of birth 1971) — see note 1
4. Biopsy primary (Біопсія первинна)
5. For a repeat biopsy, number and date of the primary one (blank)
6. Date and type of operation 05.10.26 — diagnostic laparoscopy (діагностична лапароскопія). Incisional biopsy of the gastric neoplasm (інцизійна біопсія новоутворення шлунка). Trepan biopsy of the focal lesion Sg II–III of the liver under ultrasound guidance (трепан-біопсія вогнищевого утворення Sg II–III печінки під УЗ-контролем).
7. Labelling of the material, number of objects 1) neoplasm (GIST) of the stomach; 2) liver tissue with the lesion (тканина печінки з утворенням)
8. Clinical data (blank)
9. Clinical diagnosis GIST of the stomach. Metastases to the liver (Мтс в печінку). State after therapy (стан після терапії).
Referring doctor Ostapyshen O.M. (Остапишен О.М.); signature line empty

Pathology report

Field Entry
Date the material was received 06.10.26
Number of pieces / blocks 3 pieces (шматочків), 2 blocks
Staining haematoxylin and eosin (гем-еозин), immunohistochemistry (ІГХ)
Macroscopic description 1) fragment of soft tissue 1.5 × 1 × 1.5 cm, pale yellow (блідо-жовтого кольору); 2) 2 cores of soft tissue (2 стовпчика м’яких тканин), total size 0.7 × 0.2 × 0.2 cm
Labelling of the preparations blocks No. 1–2 — material as in the referral

Immunohistochemistry (performed on the liver-lesion biopsy material — проведено на матеріалі біопсії утворення печінки)

Marker (clone) Result
CD117 / c-kit (RM359) positive reaction in the tumour cells
DOG-1 (DOG1.1) positive reaction in the tumour cells
Ki-67 (MIB-1) 2 %

Pathohistological conclusion (Патогістологічний висновок)

The fragment of the gastric lesion consists of hyalinised tissue (гіалінізованою тканиною), without viable tumour cells (без вітальних клітин пухлини), which may be a consequence of the therapy given (що може бути наслідком проведеної терапії). The liver trepan-biopsy material contains a metastasis of gastrointestinal stromal tumour (GIST), spindle-cell variant (веретеноклітинний варіант), Low Grade (written in English in the original).

Field Entry
Date of the examination 13.10.26
Pathologists Chepur N.V. (Чепур Н.В.); Kropelnytskyi V.O. (Кропельницький В.О.); signature lines empty

Notes added in translation (not part of the report)

  1. The form gives the year of birth as 1971; the patient was born on 25.04.1976 (earlier reports, e.g. the Israeli pathology report of 04.06.2023). The name and the clinical history match.
  2. Immunohistochemistry and Ki-67 were done on the liver biopsy only. No IHC is reported for the gastric fragment.
  3. No mutational (KIT/PDGFRA) analysis is reported on either sample. The report gives no mitotic count.
  4. “Focal lesion Sg II–III” is the left-lobe lesion that imaging places in segments II/III (L1 on the case site). This match is by location only; the report gives no size or image reference for the punctured lesion.
  5. “Biopsy: primary” is a form field; the earlier biopsies (2022–2023) were done at other institutions.

Translation note: plain English translation of the Ukrainian original for reference; not a certified translation.